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450 <br />BOARD OF HEALTH MEETING (SPECIAL) <br />November 26, 1984 <br />A special meeting of the Board of Health was held Monday, November 26, 1984 at <br />7:00 p.m. in Room G-1 (Recreation Office) of the Town Office Building. Members <br />present were: Mr. Mames W. Lambie, Chairman; Howard B. Asarkof, D.D.S. and <br />George A. Smith, Jr., Director of Public Health. <br />James E. Quick, Ph.D. of the Board of Health Recombinant DNA Advisory Committee <br />was also in attendance as was Mary Crawford, Lexington League of Women Voters <br />member/monitor. <br />The Meeting was called to hear a presentation by Ms. Lynn Harding, Biological <br />Safety Officer, Harvard University on RDNA Laboratory Containment/Containment <br />Procedures. <br />Ms. Harding began with an overview of infectious disease laboratory practices. <br />Existing RDNA containment procedures are derived from past, present and ongoing <br />infectious disease related experimentation. <br />Briefly. she touched on the types and percent of individuals that have experienced <br />infections in infectious disease laboratories. These included: Research 80%, <br />support 10%, clerical 6% and students 4%. <br />Also she talked about the types of labs. These included: Research, Diagnostic, <br />Industrial and teaching labs. <br />She discussed risk assessment and its importance in evaluating laboratory safety/ <br />precautions. The factors to be weighed include: Virulence, Infectious Dose, <br />Organism Viability, Route/Portal of entry and Host susceptability, e.g. <br />Healthy, immuni suppressed or ill health. <br />She discussed containment and how that containment represented the primary barrier <br />in laboratory work. Containment deals with work practices and safety equipment. <br />She related that a secondary barrier was created through laboratory design, <br />ventillation equipment, cleanable surfaces and handwashing stations. <br />The levels of containment were discussed and the different classifications <br />between cancer research, RDNA and human pathogens were mentioned as were how <br />these containment levels were identified as P1, P2, P3 and P4. <br />An explanation of these levels of containment were given and it was explained <br />how each differed as compared to one another. The explanation was provided <br />using a slide presentation. <br />After completion of the presentation Ms. Harding answered questions presented <br />by the Board of Health and others present. <br />The meeting adjourned at 9:30 p.m. The Board thanked Ms. Harding and retired. <br />